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IVIS Spectrum - Bioluminescence & Fluorescence In Vivo Imaging

MANUFACTURER Caliper Life Sciences Ltd (manufacturer's website)
MODEL In Vivo Imaging System
CONTACT 1 Mr Saimir luli
CONTACT 2 preclinicalimaging@ncl.ac.uk
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SITE City Campus


This equipment forms part of Newcastle University's Preclinical In Vivo Imaging Facility: www.ncl.ac.uk/pivi

Real time in vivo imaging The IVIS can image bioluminescence and fluorescence in up to 4 mice during a single scanning session. Images can be used to can generate high quality 3D quantitative representations of bioluminescence and fluorescence (400-900 nm) in vivo and in real time.

The software enables easy switching between fluorescence and bioluminescence modes of imaging and can allow 2 spectral images to be integrated.

An added benefit of the system is that it incorporates a topographic laser scanner and can yield for single-view, diffuse tomographic reconstructions of internal sources.


•Functional genomics ◦Expression profiles and regulation study ◦protein protein interaction ◦Apoptosis study ◦RNAi •Oncology ◦Tumour growth and metastasis ◦Tumour related gene study •Infectious disease ◦Infectious pathway ◦Molecular study •Stem cell research ◦Tracking and functional analysis •Pharmaceutical applications ◦Drug discovery (high throughput) ◦The safety and efficacy of potential drugs ◦Pharmacokinetics (PK) ◦Absorption, distribution, metabolism and excretion (ADME) •Toxicology research applications ◦Pharmaceutical toxicology ◦Chemical toxicology •Gene delivery and therapy ◦Expression kinetics and localization

Item ID #640.

Last Updated: 11th May, 2018